Low-dose inhaled versus standard dose oral form of anti-tubercular drugs: concentrations in bronchial epithelial lining fluid, alveolar macrophage and serum.

Based on clinical and histological evidence, it can be surmised that the extensive fibrous sheet was the result of fluid extravasation. Accumulation of extravasated fluid leads to fibrin deposition, which in turn ‘‘glues’’ the extensor tendons to the skin and bone restricting tendon gliding.[1] If not dispelled during the first few months, the fibrin converts into scar tissue with long-term loss of extensor tendon gliding and shortening of the dorsal joint capsules.